Protection of opiate receptors in NG108-15 against modification by N- ethylmaleimide
نویسندگان
چکیده
منابع مشابه
Interactions of forskolin and adenylate cyclase. Effects on substrate kinetics and protection against inactivation by heat and N-ethylmaleimide.
The interaction of forskolin with adenylate cyclase was studied by evaluating its effect on metal and metalATP kinetics and by measuring its protective effect when the enzyme was subjected to denaturation conditions. The solubilized calmodulinand forskolin-sensitive adenylate cyclase from brain and the particulate enzyme from platelets were inactivated upon preincubation with N-ethylmaleimide. ...
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An opioid-binding protein has recently been purified from bovine brain and cloned, and its cDNA sequence has been obtained. Indirect evidence suggests that this protein has a role in opioid-receptor function. However, because direct testing of its function by expression of its cDNA has not yet been possible and because its structure bears no resemblance to G protein-coupled receptors, the role ...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1983
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.03-01-00145.1983